In-silico model of skin



Since the enforcement of regulation prohibiting the use of animal or animal derived substances for the development and testing of consumer, cosmetic and pharmaceutical ingredients (EU regulation 76/768/EEC), there has been considerable focus on the development, evaluation and integration of alternative approaches (e.g. in silico approaches such as (Q)SARs and expert systems) for skin sensitization hazard and risk assessment. These studies open an interesting window for INTUITIVE as they could be extended to develop the in-silico model of skin to investigate the transduction mechanism in soft-skin at molecular scale. The fellow involved in this project will develop the in-silico models of skin by considering the receptors in soft skin at various depths and role of various soft materials. Here we will incorporate new findings in the synthetic material to be used for making of artificial tactile sensing skin.

Expected Results

Molecular scale mechanism of mechanoreceptors in skin for better design of tactile sensors in artificial skin.


Host institution: University of Glasgow

Enrolments (in Doctoral degree): University of Glasgow


Ravinder Dahiya, Beena Rai

Presentation of ESR4

Shashank Mishra

I am Shashank Mishra, and I am from India. I have done an integrated dual degree course (B.Tech. and M.Tech.) in Metallurgical Engineering from IIT-BHU, Varanasi. After my post-graduation, I have worked in Tata Consultancy Services R&I Labs, Pune, India as a researcher. I have experience in modelling and simulation of materials at nanoscale level using techniques like molecular dynamics simulations and coarse-grained simulations. In this project, I would be modelling the skin to investigate the transduction mechanism.